发布时间:
2026
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08
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10
Over the past decade, the main thread of gene therapy has been "rewriting hardware"—from gene supplementation to CRISPR gene editing. Their shared logic is direct modification of the DNA itself: either supplying a functional gene or cutting and rewriting genomic sequences. However, this path carries inherent risks, including genotoxicity, off-target effects, and irreversibility.In recent years, a new class of technologies has been rapidly advancing from concept to clinic—epigenome editing. Its hallmark is that it does not alter the DNA sequence but instead rewrites the "software...
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